Yashtimadhu Powder Benifits, Uses & Side Effects of Mulethi/Licorice

Yashtimadhu powder comes from the licorice sweet root, that has been in use for centuries. The origins of the perennial herb can be traced to parts of Asia and other parts of the world, like Europe. However, Mulethi has been particularly important in Ayurveda medicine. It has maintained popularity for centuries due to the countless health benefits coupled with the natural sweetness foreign in most healthy herbs.

Here’s all you need to know about Yashtimadhu powder from the main health benefits to the uses, side effects, and more.

Health benefits of Mulethi  Yashtimamadu powder

Health benefits of Mulethi / Yashtimamadu powder

Prevents diabetes

Mulethi roots contain Glabridin – a phytoestrogen proven to protect the body against diabetes. Mulethi prevents diabetes by regulating the levels of manganese superoxide dismutase – a powerful antioxidant. The herb is also rich in Amorfrutins with anti-inflammatory properties that fight diabetes-related conditions

Boosts immunity

Yashtimadhu powder also has immune system benefits. Since the powder promotes liver health, and the liver is the main detoxifying organ in the body, the powder plays a direct role in boosting immunity. These abilities can trace to the powder’s ability to reduce liver disease risks, specifically Cirrhosis, and Hepatitis C.

Mulethi can also help prevent nonalcoholic fatty liver disease regulating liver enzymes. The enzymes present in Mulethi also boost the production of macrophages and lymphocytes known to keep allergens, pollutants, and microbes away.

The powder also elevates interferon levels, which in turn stimulate superoxide dismutase to make natural hydrogen peroxide (natural antiseptic) accelerating the body’s ability to fight infections.

Reproductive health benefits

Yashtimadhu contains ingredients known to slow down the growth of the tumor. In one such study, this powder was found to shrink prostate tumors faster than medical drugs. Women also enjoy some reproductive health benefits from using Mulethi. For instance, the powder has been found to ease menopausal symptoms.

Phytoestrogenic compounds in Mulethi like Glabridin are correct hormonal imbalance responsible which are causing menopausal symptoms like depression, insomnia, hot flashes, sweating, mood swings, etc.

Skin benefits

When used topically, Mulethi (Yashtimamadu powder) has been found to ease itching, swelling, and redness caused by eczema. It’s therefore accurate to conclude that Mulethi can be used to treat eczema among other similar inflammatory skin conditions. What’s more, Mulethi lowers inflammation and boosts liver health, which results in skin benefits.

Studies also link active antioxidants in Mulethi (like licochalcone) to skin benefits such as protection from UV damage from within. Mulethi strengthens the skin’s immunity, offering protection from the sun while still supporting the benefits the skin derives from the sun.

When used topically, Mulethi is a perfect alternative to sunblock lotions packed with chemical additives, which come with side effects. To use the powder as a sunblock, you just need to mix it with some rose water and apply it.

Digestive benefits

Yashtimadhu has been found to offer significant relief from ulcers (Aphthous) within a day and complete relief within a few days. The powder offers relief from the most common mouth ulcers (Canker) known to cause pain and tenderness.

These yellow or whitish ulcers surrounded by redness can be treated by gargling a mixture of Mulethi powder and water.

To treat Canker sores, mix half a teaspoon of Mulethi powder in ¼ cup of water. Gargle four times daily to reduce canker sores resulting mainly from bacteria imbalances linked to low immunity. Mulethi has antimicrobial benefits that kill pathogenic microbes in the mouth.

The powder can also treat stomach ulcers by decreasing inflammation in the digestive system (stomach). Mulethi (Yashtimadhu) has been found to reduce gastric ulceration caused by common medication like aspirin, among other NSAIDs. Mulethi is particularly effective in dealing with pylori infection, which causes peptic ulcers. Studies have found Mulethi to contain flavonoids like Glabrene and Glabridin that inhibit H. pylori.

Mulethi has also been found to reduce colon inflammation. The herb heals inflamed mucosa and prevents mucosa ulceration of the intestines. In Ayurveda medicine, the herb is used alongside Giloy satva, bamboo manna, and Indian gooseberry to treat ulcerative colitis.

Mulethi also contains active compounds like carbenoxolone and glycyrrhizin known to relieve heartburn, stomach discomfort, constipation, acidity, heartburn, and many other common stomach problems. The herb is also administered as a laxative to stimulate bowel movements.

Antiaging benefits

Mulethi is a natural dihydrotestosterone blocker. It is also an anti-androgen. Androgens are known to cause excessive dihydrotestosterone (DHT). When DHT isn’t metabolized efficiently, it can cause patterned baldness by shrinking and lowering blood supply to hair follicles. Mulethi has shown phytoestrogen abilities that prevent excessive DHT.

Treating chronic fatigue

Yashtimadhu can also get rid of chronic fatigue. Stress disorders are very common today regardless of the trigger (mental, physical, or environmental factors). When you get stressed, your adrenal glands go into overdrive in an effort to control the stress. The stress can be imaginary (mental) or physical. Both types of stress prompt the adrenal glands to increase the level of the stress hormone cortisol.

When stress is prolonged, the adrenal glands become fatigued, reducing the amount of energy being produced. This eventually causes chronic fatigue. Mulethi is among the most effective natural herbs known to regulate cortisol levels restoring back energy.

Respiratory health benefits

Mulethi can also relieve sore throat due to the herb’s bronchodilator and expectorant properties. The herb can treat bronchitis, cough, and reduce the effects of respiratory conditions like chronic asthma. You can mix Mulethi powder with water, ginger juice, or make tea to soothe asthma or treat respiratory conditions like bronchitis.

Uses of Mulethi/Yashtimadhu powder

You can use Mulethi powder in several ways. They most notable include:

Uses of MulethiYashtimadhu powder

As a sweetener: Mulethi is used to sweeten beverages and candy commercially. As a sweetener, it’s not advisable to exceed 30mg/ml (glycyrrhizic acid). Exceeding this limit can result in unwanted side effects.

As a topical ointment: Mulethi can also be used as a topical ointment to offer skin benefits discussed above. Mulethi powder is popular in health food and online specialty stores for this reason. The powder can treat eczema, acne, and related skin conditions.

As a tea: Mulethi powder can also be taken as a tea. Mulethi plant roots and leaves are dried and crushed into a powder tea. You can find tea in health food stores locally or online. Taking Mulethi tea can boost your digestive, adrenal, and respiratory health. The tea can cure common respiratory illnesses and detox the body. However, you shouldn’t consume over 8 ounces of tea a day.

Hair Removal: Mulethi Powder can also use as facial hair removal. Learn more about how to use Mulethi as hair removal.

Important: Mulethi powder can be packaged and ingested orally like capsules for other health benefits i.e., digestive system health. If that’s the case, you shouldn’t exceed 75 mg per day.

Mulethi Powder Side Effects

Mulethi powder can cause some side effects if taken excessively. The most notable side effects include;

Mulethi Powder Side Effects

Lowering potassium levels: Too much Mulethi powder can lower potassium levels in the body, causing conditions like hypokalemia (muscle weakness). Several studies have shown that ingesting a lot of Mulethi powder over 14 or more days can lead to metabolism abnormalities and fluid retention associated with low potassium levels.

High blood pressure problems: Consuming too much Mulethi powder can result in high blood pressure, heartbeat irregularities, and swelling. Mulethi-flavored products mimic natural Mulethi. However, some contain glycyrrhizic acid.

Too much ingestion of such products can cause hypertension. Young children and pregnant/breastfeeding mothers are advised to avoid Mulethi powder for this reason. Individuals with hypertension should avoid Mulethi, as well. The powder contains glycyrrhizinic acid, which produces chain reactions that cause high blood pressure.

Low potassium levels: Side effects like low potassium levels are caused by the presence of glycyrrhetinic acid. If the powder has this acid, it can cause renal 2-beta-hydroxysteroid de-hydrogenase. It can also stimulate mineralocorticoid receptors. This side effect disappears on its own (within three weeks), in most cases returning blood pressure back to normal.

Bloating and fluid retention: The powder causes the above side effects and more such as bloating and fluid retention mostly when taken alongside other additives or when an unnatural form is used. The side effects also occur after prolonged use i.e., when taken regularly in high dosage for months.

Other side effects include hyper mineralocorticoid ism, which causes hypersensitive encephalopathy and moderate hypertension.

Dosage and safety

Mulethi causes side effects like high blood pressure when the powder is taken in excess i.e., over 10g daily. Studies about this side effect have been conducted using high doses (50-100mg). In typical cases, the therapeutic dosage doesn’t exceed 10g.


Mulethi powder has been a powerful herb for centuries. The health benefits show why the herb is still in use today. Including Mulethi powder is bound to offer numerous health benefits ranging from improved immunity, respiratory and digestive system health to better skin and energy levels.

The powder will also boost your reproductive system health and offer other benefits. Most importantly, you can use Mulethi in many ways. However, you must adhere to the recommended dosage to avoid negative side effects.


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